Using the D-BEST Reference Model to Compare Italian and Polish Digital Innovation Hubs

In recent years, the increasing importance of Digital Innovation Hubs (DIHs) in supporting manufacturing Small and Medium Enterprises (SMEs) has been widely studied and several works listing lessons learnt and success stories have been published. To further foster the impact of these entities on the SMEs’ environment, The European Commission has recently introduced the Smart Specialisation Platform, which contains a web service returning to its users a geo-distributed list of DIHs, allowing the user also to cluster and visualise them according to some pre-defined filters, such as the types of technologies employed. The data provided by this platform has been downloaded and a secondary data analysis, based on the websites of the DIHs has been carried on to frame the single DIHs according to the axes of the D-BEST methodology. A comparative analysis with respect to the Italian and Poland situation completes the study, to understand eventual differences and affinities among the two countries

Digital Innovation Hubs Proposing Digital Platforms to Lead the SMEs Digital Transition

DIHs could offer a marketplace and play the role of a broker facilitating cooperation and networking among important stakeholders, harmonizing companies with customers and providing European connections as well. In this framework, DIHs express an increasing need for having platforms bolstering users-producers transactions, fostering to detect what is needed, by grouping a large variety of services and goods together. This paper presents the main platforms grounded on the D-BEST reference model developed by different networks of DIHs. The main characteristics of each of them have been detected and the differences among them unveiled

Breakdown of the mean-field approximation in a wealth distribution model

One of the key socioeconomic phenomena to explain is the distribution of wealth. Bouchaud and M\'ezard have proposed an interesting model of economy [Bouchaud and M\'ezard (2000)] based on trade and investments of agents. In the mean-field approximation, the model produces a stationary wealth distribution with a power-law tail. In this paper we examine characteristic time scales of the model and show that for any finite number of agents, the validity of the mean-field result is time-limited and the model in fact has no stationary wealth distribution. Further analysis suggests that for heterogeneous agents, the limitations are even stronger. We conclude with general implications of the presented results.Comment: 11 pages, 3 figure

Financial development and economic growth : long-run equilibrium and transitional dynamics

We analyze the impact of financial development on economic growth. Differently from previous studies that focus mainly on balanced growth path outcomes, we also analyze the transitional dynamics of our model economy by using a finance-extended Uzawa-Lucas framework where financial intermediation affects both human and physical capital accumulation. We show that, under certain rather general conditions, economic growth may turn out to be non-monotonically related to financial development (as suggested by the most recent empirical evidence) and that too much finance may be detrimental to growth. We also show that the degree of financial development may affect the speed of convergence, which suggests that finance may play a crucial role in determining the length of the recovery process associated with exogenous shocks. Moreover, in a special case of the model, we observe that, under a realistic set of parameters, social welfare decreases with financial development, meaning that even when finance positively affects economic growth the short term costs associated with financial activities more than compensate their long run benefits

Design of a CZT Gamma-Camera for GRB and Fast Transient Follow-up: a Wide-Field-Monitor for the EDGE Mission

The success of the SWIFT/BAT and INTEGRAL missions has definitely opened a new window for follow-up and deep study of the transient gamma-ray sky. This now appears as the access key to important progresses in the area of cosmological research and deep understanding of the physics of compact objects. To detect in near real-time explosive events like Gamma-Ray bursts, thermonuclear flashes from Neutron Stars and other types of X-ray outbursts we have developed a concept for a wide-field gamma-ray coded mask instrument working in the range 8-200 keV, having a sensitivity of 0.4 ph cm-2 s-1 in 1s (15-150 keV) and arcmin location accuracy over a sky region as wide as 3sr. This scientific requirement can be achieved by means of two large area, high spatial resolution CZT detection planes made of arrays of relatively large (~1cm2) crystals, which are in turn read out as matrices of smaller pixels. To achieve such a wide Field-Of-View the two units can be placed at the sides of a S/C platform serving a payload with a complex of powerful X-ray instruments, as designed for the EDGE mission. The two units will be equipped with powerful signal read out system and data handling electronics, providing accurate on-board reconstruction of the source positions for fast, autonomous target acquisition by the X-ray telescopes.Comment: 9 pages, 7 figures, SPIE Conference on UV, X-ray, and Gamma-Ray Instrumentation for Astronomy, San Diego 26-30 August 200

Entrepreneurs, Chance, and the Deterministic Concentration of Wealth

In many economies, wealth is strikingly concentrated. Entrepreneurs–individuals with ownership in for-profit enterprises–comprise a large portion of the wealthiest individuals, and their behavior may help explain patterns in the national distribution of wealth. Entrepreneurs are less diversified and more heavily invested in their own companies than is commonly assumed in economic models. We present an intentionally simplified individual-based model of wealth generation among entrepreneurs to assess the role of chance and determinism in the distribution of wealth. We demonstrate that chance alone, combined with the deterministic effects of compounding returns, can lead to unlimited concentration of wealth, such that the percentage of all wealth owned by a few entrepreneurs eventually approaches 100%. Specifically, concentration of wealth results when the rate of return on investment varies by entrepreneur and by time. This result is robust to inclusion of realities such as differing skill among entrepreneurs. The most likely overall growth rate of the economy decreases as businesses become less diverse, suggesting that high concentrations of wealth may adversely affect a country's economic growth. We show that a tax on large inherited fortunes, applied to a small portion of the most fortunate in the population, can efficiently arrest the concentration of wealth at intermediate levels

The LSD1-Type Zinc Finger Motifs of Pisum sativa LSD1 Are a Novel Nuclear Localization Signal and Interact with Importin Alpha

Background: Genetic studies of the Arabidopsis mutant lsd1 highlight the important role of LSD1 in the negative regulation of plant programmed cell death (PCD). Arabidopsis thaliana LSD1 (AtLSD1) contains three LSD1-type zinc finger motifs, which are involved in the protein-protein interaction. Methodology/Principal Findings: To further understand the function of LSD1, we have analyzed cellular localization and functional localization domains of Pisum sativa LSD1 (PsLSD1), which is a homolog of AtLSD1. Subcellular localization analysis of green fluorescent protein (GFP)-tagged PsLSD1 indicates that PsLSD1 is localized in the nucleus. Using a series of GFP-tagged PsLSD1 deletion mutants, we found that the three LSD1-type zinc finger motifs of PsLSD1 alone can target GFP to the nucleus, whereas deletion of the three zinc finger motifs or any individual zinc finger motif causes PsLSD1 to lose its nuclear localization, indicating that the three zinc finger motifs are necessary and sufficient for its nuclear localization. Moreover, site-directed mutagenesis analysis of GFP-tagged PsLSD1 indicates that tertiary structure and basic amino acids of each zinc finger motif are necessary for PsLSD1 nuclear localization. In addition, yeast two-hybrid, pull-down, and BiFC assays demonstrate that the three zinc finger motifs of PsLSD1 directly bind to importin alpha in vitro and in vivo. Conclusions/Significance: Our data demonstrate that the LSD1-type zinc finger motifs of PsLSD1 are a novel nuclear localization signal and directly bind to importin alpha, and suggest that the nuclear import of LSD1 may rely on the interaction between its zinc finger motifs and importin alpha. Moreover, the nuclear localization of PsLSD1 suggests that LSD1 may function as a transcription regulator involved in negatively regulating PCD.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000292929500042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Multidisciplinary SciencesSCI(E)PubMed11ARTICLE7e22131